Close this search box.

Your cart

0 products

No products in the cart.

MEDICAL LETTER: John R. Lee M.D. Volume III (December 2000)

As women near middle age, may acquire a “tummy” that stays put regardless of diet and exercise. Thanks to some new research, the possible  cause of this unwanted bulge may encourage women to reduce their stress levels.

According to Elissa S. Epel and colleagues at Yale, stress can increase abdominal fat, even in premenopausal women who are otherwise lean.  The researchers found that such women were found to have higher stress-related cortisol levels.  This correlates with the central (abdominal) fat deposition that is common in Cushing’s disease, a disease of elevated serum cortisol.

The results observed by the yale researchers should not be surprising. Short-term response to stress involves adrenaline production. Long-term stress increases cortisol, which further inhibits progesterone receptors. Thus, these two mechanisms result in estrogen dominance as well as higher cortisol levels with the net effect of excess central fat deposition regardless of diet and exercise.

For stressed-out premenopausal women with increased abdominal fat, stress reduction and stress management techniques are certainly indicated, along with progesterone supplementation if estrogen dominance is evident.



John R. Lee M.D. – Medical Letter, Volume III, January 2000 – December 2000)

Epel ES, et al, “Stress may cause excess abdominal fat in otherwise slender women,” Psycho-somatic Medicine, September/October 2000.

Sosa ZY, Casias M, Rastrilla AM, Aguado L, “Adrenergic influences on coeliac ganglion affect the release of progesterone from cycling ovaries: characterization of an invitro system,” Endocrinology 2000; 166(2): 307-318.

Add Your Heading Text Here

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

Share the love

Keep reading

National Stress Awareness Month, 30 Ways Stress Can Affect Your Body, stress relief, natural stress relief, GABA L-Theanine, sleep, anxiety, depression, anger, sadness, insomnia, overworked
By Daniel Lyons
April 4 2024
30 Ways Stress Can Affect Your Body

Stress is a term you’re likely familiar with. You may also know exactly what stress feels like. However, what does stress exactly mean? This body re...

Read more
Nutra relief liposomal creams liposomal delivery technology LDT vitamin shop nootropic workout nutrition natural vitamins topical creams skin cream anxiety relief stress relief depression mood related disorders insomnia dementia Alzheimer’s Disease support high blood pressure cardiovascular support heart health post-traumatic stress disorder PTSD substance dependence autism support ADHD support improves focus relieves symptoms of PMS addiction support brain supplement chronic fatigue support deep sleep weight loss support mental clarity women’s health men’s health
By dnutrarelief
April 3 2024
Reducing ANXIETY Naturally

When you’re under stress and anxiety for days — or even weeks or months — you’re at risk for numerous health effects. Such risks may extend to...

Read more
Sleep, Circadian Rhythm, and Mental Health
By Daniel Lyons
April 2 2024
Sleep, Circadian Rhythm, and Mental Health

Neuroscience News Summary: A new study highlights the critical link between sleep, circadian rhythms, and psychiatric disorders, suggesting that distu...

Read more